The Society for Mathematical Biology is governed by its Officers and Board of Directors, elected by the membership. The Bylaws provide regulatory procedures to govern the Society.
Officers:
 President (2021–2023) Heiko Enderling Moffitt Cancer Center |
 President Elect – serving as vice president (2023-2025) Jane Heffernan York University |
 Secretary (2020-2023) Gibin Powathil Swansea University |
 Treasurer (2020-2023) Jana Gevertz The College of New Jersey |
Board of Directors:
 (2016–2024) Ruth Baker University of Oxford |
 (2020–2024) Zhilan Feng Purdue University |
 (2022-2026) Padmini Rangamani University of California San Diego |
 (2022-2026) Amina Eladdadi The College of St Rose |
(2018-2022) |
 (2016-2024) Amber Smith University of Tennessee Health Science Center |